HORDB

ID: hor000089
Uniprot ID: P15444
Protein name: Neurophysin 1
Gene name: NA
Organism: Struthio camelus (Common ostrich)
Family: Vasopressin/oxytocin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Struthio (genus), Struthionidae (family), Struthioniformes (order), Palaeognathae (superorder), Aves (class), Coelurosauria, Theropoda, Saurischia, Dinosauria, Archosauria, Archelosauria, Sauria, Sauropsida, Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005185 neurohypophyseal hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: AVLDMDIRKCMPCGPRNKGHCFGPNICCGEELGCYFGTSETLRCQEENFLPTPCESGRKPCGNNEGSCAASGICCSNEGCMVDSSCDQEVMFP
Length: 93
Propeptide: AVLDMDIRKCMPCGPRNKGHCFGPNICCGEELGCYFGTSETLRCQEENFLPTPCESGRKPCGNNEGSCAASGICCSNEGCMVDSSCDQEVMFP
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P15444-F1.pdb

hor000089_AF2.pdb

hor000089_ESM.pdb

Mass:	1161249	Formula:	C406H636N118O139S18
Absent amino acids:	W	Common amino acids:	C
pI:	4.27	Basic residues:	8
Polar residues:	42	Hydrophobic residues:	17
Hydrophobicity:	-32.8	Boman Index:	-15816
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	41.94
Instability Index:	5239.78	Extinction Coefficient cystines:	2365
Absorbance 280nm:	25.71

PubMed ID: 3436699
Title: Complete Amino Acid Sequence of a VLDV-type Neurophysin From Ostrich Differs Markedly From Known Mammalian Neurophysins